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Opinion articles: topical or controversial areas that do not warrant a full review (500-1000 words).

Case studies in biological research applied to clinical practice (2000-5000 words).

Problem solving protocols: protocols for solving a specific problem using different sets of programs (2000-5000 words).

Do not include new results from your own work (2000-7000 words)

Reviews: surveys of previously published research in specified areas giving an overview and making recommendations for the optimal approaches to problem solving.

Submissions of the following types are accepted for review in the Journal: As the science advances details of what is important changes and the Editors, Editorial Board and Reviewers will be flexible in their policies. In bioinformatics there are typically multiple different tools and parameter settings that can be selected for a given problem and these should be evaluated and compared to one another using simulation if appropriate and empirical real datasets if available, preferably by authors who are not originators of the software.

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We encourage papers that provide an independent evaluation of software tools for common tasks. There should be more studies focussing on the replicability and reproducibility of bioinformatics methodologies and realistic sample sizes required for this. Articles focusing on illuminating bottleneck problems in important bioinformatics approaches will be especially helpful to readers. Ontologies for semantic-based analysis of molecular data and interaction networks, methods and tools for the automatic or semiautomatic annotation of biological data with terms extracted from ontologies, and methods and tools for enrichment analysis are all relevant to the objectives. Methodological approaches of interest include software comparison and benchmarking, data cleaning and curation, accuracy of predicted and extracted information, ontologies and text-mining, solutions that allow for the large-scale analysis of biological data in reasonable time (high performance computing solutions and cloud systems), standards, training and change management activities, and the determination of causal relationships from data. We do not publish work on new methods that have not yet been described elsewhere except in the context of a wider review of that specific subject area. Descriptions of existing analytical solutions of biological problems should be transparent and user friendly and may include mathematical and statistical methods for high dimensional and high throughput data. The underlying concepts must be clearly explained along with the selection of the correct tools for a problem, their limitations, and the interpretation of the results.

Reviews may be broader or more narrowly focussed but must cover a variety of approaches to a very well specified biological problem or research area. We publish reviews of clearly defined subject areas for both experimental biologists and for bioinformatics specialists. The Editors welcome the submission of review articles and case studies for publication. Reviews of the related education and training in the biomedical sciences are included in the scope. The journal provides topical reviews of new methodologies as they become established. Instead, the rate-limiting step is the analysis and interpretation of data. Large-scale instrumentation and computerisation is reducing the time that needs to be spent in the laboratory. This includes all areas of genomics, proteomics, lipidomics, glycomics, metabolomics, interactomics and network biology, imaging, systems biology, phenomics, chemoinformatics, computational biology and clinical/medical informatics that have a molecular foundation to the study. The aim of Briefings in Bioinformatics is to provide an indispensable resource for the experimental practitioner seeking awareness of the disparate sources of data and analytical tools of contemporary biology, biotechnology and medicine based on the molecular level. Author Self-Archiving/Public Access Policyįor information about this journal's policy, please visit our Author Self-Archiving policy page.

All print editions have been discontinued. Authors are able to access their published articles and content via the Oxford Academic platform.

Journal online-only since 2018īriefings in Bioinformatics is published online-only. Please contact Alison Bentley in the Editorial Office at with any submission queries in the first instance. *Authors will be asked to 'sign' their licence to publish online* Author Self-Archiving/Public Access Policy